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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EIF2AK4
All Species:
9.09
Human Site:
S1410
Identified Species:
20
UniProt:
Q9P2K8
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9P2K8
NP_001013725.2
1649
186838
S1410
S
V
G
Q
M
S
M
S
R
A
I
N
L
T
Q
Chimpanzee
Pan troglodytes
XP_001140245
1649
186793
S1410
S
V
G
Q
M
S
M
S
R
A
I
N
L
T
Q
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_535431
1633
184740
I1387
I
D
K
I
S
A
A
I
L
N
M
E
E
P
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9QZ05
1648
186468
S1409
S
V
G
Q
M
S
M
S
R
A
I
N
L
T
Q
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518247
1608
180821
P1369
S
A
G
Q
L
S
M
P
R
A
I
G
I
T
Q
Chicken
Gallus gallus
XP_421203
1656
188583
G1416
S
V
G
Q
M
S
M
G
R
A
I
N
I
V
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002667149
1483
168725
V1245
L
T
L
K
L
Q
V
V
V
N
L
G
L
V
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001120977
1130
130476
A892
C
K
Y
G
I
N
V
A
I
S
C
M
D
N
H
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785160
1605
181469
R1367
S
I
G
R
P
K
K
R
P
T
M
D
V
L
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LX30
1241
140303
D1003
V
A
S
R
F
C
G
D
A
D
Q
A
L
P
R
Baker's Yeast
Sacchar. cerevisiae
P15442
1659
190175
D1405
S
F
S
N
S
L
L
D
T
I
G
V
T
I
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
N.A.
89.7
N.A.
90.5
N.A.
N.A.
74.7
72.3
N.A.
52.6
N.A.
N.A.
27.9
N.A.
40.4
Protein Similarity:
100
99.9
N.A.
94.3
N.A.
94.9
N.A.
N.A.
84.4
84.5
N.A.
67.4
N.A.
N.A.
44
N.A.
59.4
P-Site Identity:
100
100
N.A.
0
N.A.
100
N.A.
N.A.
66.6
80
N.A.
6.6
N.A.
N.A.
0
N.A.
13.3
P-Site Similarity:
100
100
N.A.
13.3
N.A.
100
N.A.
N.A.
80
86.6
N.A.
33.3
N.A.
N.A.
33.3
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.5
26.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
39.7
46.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
19
0
0
0
10
10
10
10
46
0
10
0
0
10
% A
% Cys:
10
0
0
0
0
10
0
0
0
0
10
0
0
0
0
% C
% Asp:
0
10
0
0
0
0
0
19
0
10
0
10
10
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
10
10
0
0
% E
% Phe:
0
10
0
0
10
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
55
10
0
0
10
10
0
0
10
19
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% H
% Ile:
10
10
0
10
10
0
0
10
10
10
46
0
19
10
0
% I
% Lys:
0
10
10
10
0
10
10
0
0
0
0
0
0
0
0
% K
% Leu:
10
0
10
0
19
10
10
0
10
0
10
0
46
10
10
% L
% Met:
0
0
0
0
37
0
46
0
0
0
19
10
0
0
0
% M
% Asn:
0
0
0
10
0
10
0
0
0
19
0
37
0
10
0
% N
% Pro:
0
0
0
0
10
0
0
10
10
0
0
0
0
19
0
% P
% Gln:
0
0
0
46
0
10
0
0
0
0
10
0
0
0
46
% Q
% Arg:
0
0
0
19
0
0
0
10
46
0
0
0
0
0
10
% R
% Ser:
64
0
19
0
19
46
0
28
0
10
0
0
0
0
0
% S
% Thr:
0
10
0
0
0
0
0
0
10
10
0
0
10
37
0
% T
% Val:
10
37
0
0
0
0
19
10
10
0
0
10
10
19
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _